Title:
前立腺癌バイオマーカー
Document Type and Number:
Japanese Patent JP2006509186
Kind Code:
A
Abstract:
Protein biomarkers that may advantageously be utilized in diagnosing prostate cancer, benign prostate hyperplasia or to make a negative diagnosis are described. Accordingly, in one aspect of the invention, methods for aiding in, or otherwise making, a diagnosis of prostate cancer or benign prostate hyperplasia are provided. In one form of the invention, a method includes detecting various protein biomarkers of defined molecular weight and correlating the detection to a diagnosis of prostate cancer, benign prostate hyperplasia or to a negative diagnosis. In yet another aspect of the invention, kits are provided that may be utilized to detect the biomarkers described herein. In a further of the invention, methods of using a plurality of classifiers to make a probable diagnosis of prostate cancer of benign prostate hyperplasia are provided. In certain forms of the invention, the methods include use of a boosted decision tree analysis. Various computer readable media are also provided.
Inventors:
Wright, George L., Juniors
Adam, Bao Lin
Ku, Insheng
Adam, Bao Lin
Ku, Insheng
Application Number:
JP2004541437A
Publication Date:
March 16, 2006
Filing Date:
May 09, 2003
Export Citation:
Assignee:
Eastern Virginia Medical School
Fred Hutchinson Cancer Research Center
Fred Hutchinson Cancer Research Center
International Classes:
G01N33/574; A61B1/00; B01J20/281; C12Q1/68; C12Q1/70; G01N27/62; G01N27/64; G01N30/00; G01N30/26; G01N30/88; G01N33/53; G01N33/68; G16B20/00; G16B40/20; G06F19/00; A61B
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita