Title:
免疫反応の変化を生じるプロテアーゼ、ならびにその製造および利用方法
Document Type and Number:
Japanese Patent JP2005535284
Kind Code:
A
Abstract:
The present invention provides novel protein variants that exhibit reduced immunogenic responses, as compared to the parental proteins. The present invention further provides DNA molecules that encode novel variants, host cells comprising DNA encoding novel variants, as well as methods for making proteins less allergenic. In addition, the present invention provides various compositions that comprise these proteins that are less immunogenic than the wild-type proteins.
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Inventors:
Esther, David A.
Harding, Fiona A
Harding, Fiona A
Application Number:
JP2003558027A
Publication Date:
November 24, 2005
Filing Date:
December 20, 2002
Export Citation:
Assignee:
Genenco International Inc.
Esther, David A.
Harding, Fiona A
Esther, David A.
Harding, Fiona A
International Classes:
C12N15/09; A61K8/00; A61K8/33; A61K8/34; A61K8/36; A61K8/365; A61K8/42; A61K8/64; A61K8/66; A61K8/72; A61K8/86; A61K8/89; A61K8/891; A61Q11/00; A61Q11/02; A61Q19/00; A61Q19/10; C11D3/386; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/54; C12N9/56; (IPC1-7): C12N15/09; A61K7/00; A61K7/28; A61K7/30; A61K7/48; A61K7/50; C11D3/386; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/56
Attorney, Agent or Firm:
Yuzo Yamazaki
Naoto Sugiyama
Shirogane Expo
Takako Hoshi
Toshiaki Akamatsu
Kazuki Shigemori
Naoto Sugiyama
Shirogane Expo
Takako Hoshi
Toshiaki Akamatsu
Kazuki Shigemori