To provide an effective preparation for the administration of a ginseng, its essence, ginseng component, their metabolites or their salts useful as a brain cell-protecting agent or nerve cell injury-treating agent, and especially useful for the prevention and treatment of brain/nerve diseases, heart diseases, etc.
This protecting agent for brain cells or nerve cells consists of a medicinal composition consisting of preferably a low concentration ginseng, its essence, ginseng components, their metabolites or their salts, and accelerates the expression of a brain cell death-inhibitory gene product, BC1-XL protein, or has an activity, of inhibiting apoptosis or apoptosis like cell death. Further, preferably an orally administering preparation or an intravenously administering preparation consisting preferably of a low concentration ginseng, its essence, ginseng components, their metabolites or their salts, e.g. a red ginseng powder or its components is provided.
MAEDA SHINJI
TANAKA JUNYA
NAKADA KIMIHIKO
| JPH04504414A | 1992-08-06 |
| WO1999009837A1 | 1999-03-04 |