Title:
Protein OSTA cis-regulatory element
Document Type and Number:
Japanese Patent JP6208122
Kind Code:
B2
Abstract:
The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
Inventors:
Foley, Megan
Bradley Tate
Karen, Matthew
Bradley Tate
Karen, Matthew
Application Number:
JP2014510469A
Publication Date:
October 04, 2017
Filing Date:
May 10, 2012
Export Citation:
Assignee:
Proteostasis Therapeutics, Incorporated
International Classes:
C07D209/14; C07D401/06
Domestic Patent References:
| JP11503445A | ||||
| JP2007519631A | ||||
| JP8225535A | ||||
| JP2001151771A | ||||
| JP2002510622A | ||||
| JP10508321A | ||||
| JP2010518125A | ||||
| JP2003501476A | ||||
| JP11503758A |
Foreign References:
| WO2010139982A1 | ||||
| WO2009127686A1 | ||||
| WO2002000621A1 | ||||
| WO2010006234A2 | ||||
| WO2005121175A2 | ||||
| GB1410783A | ||||
| GB1073521A | ||||
| WO2005007141A2 |
Other References:
Gadaginamath, Guru S. et al.,Synthesis and antimicrobial activity of 4-isogramines, 4-aryl-thiomethyl and 3-aminoacetyl derivatives of 2-methylindoles,Revue Roumaine de Chimie,1995年,40(3),pp. 265-273
Gadaginamath, G. S. et al.,Synthesis and antimicrobial activity of novel 3-thiazolyl/imidazo(2,1-b)-1,3,4-thiadiazolyl/anilinoacetyl/phenoxyacetyl indole derivatives,Indian Journal of Heterocyclic Chemistry,1999年,9(1),pp. 33-38
Kumar, Dalip et al.,A facile and regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles using click chemistry,Tetrahedron Letters,2009年,50(18),pp. 2065-2068
STN International,File REGISTRY [online],2011年 3月 3日,検索日:2016年1月13日,RN 1266216-33-4, RN 1266208-38-1, RN 1266193-66-1, RN 1266184-43-3, RN 1266168-16-4, RN 1266155-14-9, RN 1266153-33-6, RN 1266150-22-4, RN 1266137-42-1, RN 1266131-49-0
Gadaginamath, G. S. et al.,Synthesis and antimicrobial activity of novel 3-thiazolyl/imidazo(2,1-b)-1,3,4-thiadiazolyl/anilinoacetyl/phenoxyacetyl indole derivatives,Indian Journal of Heterocyclic Chemistry,1999年,9(1),pp. 33-38
Kumar, Dalip et al.,A facile and regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles using click chemistry,Tetrahedron Letters,2009年,50(18),pp. 2065-2068
STN International,File REGISTRY [online],2011年 3月 3日,検索日:2016年1月13日,RN 1266216-33-4, RN 1266208-38-1, RN 1266193-66-1, RN 1266184-43-3, RN 1266168-16-4, RN 1266155-14-9, RN 1266153-33-6, RN 1266150-22-4, RN 1266137-42-1, RN 1266131-49-0
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Kaoru Takahashi
Nao Oda
Kaoru Takahashi