Title:
NMR試験のための蛋白質の部位特異的標識
Document Type and Number:
Japanese Patent JP2008513806
Kind Code:
A
Abstract:
Methods of producing and/or analyzing spectroscopically labeled proteins, e.g., proteins site-specifically labeled with NMR active isotopes, spin-labels, chelators for paramagnetic metals, and the like, are provided. The labeled proteins are produced in translation systems including orthogonal aminoacyl tRNA synthetase/tRNA pairs. Methods for assigning NMR resonances, e.g., methods using isotopically labeled proteins, are also provided.
Inventors:
Alexander Dieters
Bernhard Har. Gaier Stanger
Peter G. Schultz
Bernhard Har. Gaier Stanger
Peter G. Schultz
Application Number:
JP2007533646A
Publication Date:
May 01, 2008
Filing Date:
September 21, 2005
Export Citation:
Assignee:
THE SCRIPPS RESEARCH INSTITUTE
IR M LLC
IR M LLC
International Classes:
C12P21/00; G01R33/465; G01R33/30
Domestic Patent References:
| JPH05236987A | 1993-09-17 |
Foreign References:
| WO2002086075A2 | 2002-10-31 | |||
| WO2002085923A2 | 2002-10-31 |
Attorney, Agent or Firm:
Kazuho Kawarada