PROTEIN ENCODED BY POLYNUCLEIC ACID OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV)

Title:

PROTEIN ENCODED BY POLYNUCLEIC ACID OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV)

Document Type and Number:

Japanese Patent JP2011103883

Kind Code:

A

Abstract:

To provide a method of protecting a pig from a porcine reproductive and respiratory syndrome virus (PRRSV), a method of treating a pig infected by a PRRSV, and a method of detecting a PRRSV in a pig.

The present invention provides: at least one polypeptide selected from the group consisting of proteins encoded by one or more open reading frames (ORF's) of an Iowa strain of PRRSV, antigenic regions of such proteins which are at least 5 amino acids in length and which effectively protect a porcine host against a subsequent challenge with a PRRSV isolate, and combinations thereof in which amino acids non-essential for antigenicity may be conservatively substituted; a vaccine comprising an effective amount of such a protein; and antibodies which specifically bind to such a protein.

Inventors:

PAUL PREM S
ZHANG YANJIN

Application Number:

JP2010256079A

Publication Date:

June 02, 2011

Filing Date:

November 16, 2010

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIV IOWA STATE RES FOUND INC (US)

International Classes:

C12N15/09; A61K39/12; A61K48/00; A61P31/04; A61P31/12; A61P31/14; A61P31/20; C07K7/08; C07K14/00; C07K14/01; C07K14/08; C07K16/00; C07K16/08; C07K16/10; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N7/00; C12N7/01; C12N15/40; C12P21/02; C12P21/08; C12Q1/68; G01N33/53; G01N33/569; A61K38/00; A61K39/00

Domestic Patent References:

JPH07138186A

1995-05-30

Other References:

JPN6008060635; Ｊ．　Ｇｅｎ．　Ｖｉｒｏｌ．ｖｏｌ．７５，　ｎｏ．７, 1994, ｐｐ．１７９５-１８０１
JPN6009043656; Ａｒｃｈ．　Ｖｉｒｏｌ．ｖｏｌ．１４０，　ｎｏ．８, 1995, ｐｐ．１４０５-１４１８
JPN6009043655; Ａｒｃｈ．　Ｖｉｒｏｌ．ｖｏｌ．１４０，　ｎｏ．７, 1995, ｐｐ．１３１３-１３１９
JPN6009043658; Ｊ．　Ｖｅｔ．　Ｄｉａｇｎ．　Ｉｎｖｅｓｔ．ｖｏｌ．８，　ｎｏ．１, 1996, ｐｐ．１１-２０
JPN6009043660; Ｊ．　Ｖｅｔ．　Ｄｉａｇｎ．　Ｉｎｖｅｓｔ．ｖｏｌ．８，　ｎｏ．３, 1996, ｐｐ．３７４-３８１
JPN6008060642; Ｖｅｔ．　Ｉｍｍｕｎｏｌ．　Ｉｍｍｕｎｏｐａｔｈｏｌ．ｖｏｌ．５９，　ｎｏ．３-４, 1997, ｐｐ．３２３-３３５
JPN6008060638; Ｊ．　Ｇｅｎ．　Ｖｉｒｏｌ．ｖｏｌ．７６，　ｎｏ．１２, 1995, ｐｐ．３１８１-３１８８
JPN6011017762; Ａｒｃｈ．　Ｖｉｒｏｌ．ｖｏｌ．１４０，　ｎｏ．４, 1995, ｐｐ．７４５-７５５
JPN6013042516; ＦＡＳＥＢ　Ｊ．ｖｏｌ．５，　ｎｏ．１０, 1991, ｐｐ．２４２７-２４３６
JPN6013042517; Ｊ．　Ｇｅｎ．　Ｖｉｒｏｌ．ｖｏｌ．７２，　ｎｏ．１, 1991, ｐｐ．１１７-１２４
JPN6013042521; Ｊ．　Ｇｅｎ．　Ｖｉｒｏｌ．ｖｏｌ．７２，　ｎｏ．８, 1991, ｐｐ．１８３５-１８４３
JPN6013042522; Ａｒｃｈ．　Ｖｉｒｏｌ．ｖｏｌ．１４２，　ｎｏ．３, 1997, ｐｐ．５２３-５３４

Attorney, Agent or Firm:

Hirohito Katsunuma
Yukitaka Nakamura
Noritaka Yokota
Takeyasu Ito
Omori Miko

Previous Patent: CELL CULTURE APPARATUS, AND METHOD AND PROGRAM FOR CULTURING CELL

Next Patent: HUMAN HEPATIC PROGENITOR CELL AND METHOD OF USE THEREOF