Title:
PROTEIN IMPARTING INDUCTIVE GLYCOPEPTIDE RESISTANCE ESPECIALLY TO GRAM-POSITIVE BACTERIA
Document Type and Number:
Japanese Patent JP2004065257
Kind Code:
A
Abstract:
To provide a method for screening an active molecule for treating infection caused by a gram-positive coccus especially caused by enterococcus and especially for screening antibiotics.
The protein Van B concerning to glycopeptide resistance of gram-positive bacteria, inducible by vancomycin and non-inducible by teicoplanin, especially to vancomycin resistance is provided, and also, the application of a nucleotide fragment of a gene van B for detecting glycopeptide resistance is provided.
Inventors:
ARTHUR MICHEL (FR)
DUTKA-MALEN SYLVIE (FR)
EVERS STEFAN (FR)
COURVALIN PATRICE (FR)
DUTKA-MALEN SYLVIE (FR)
EVERS STEFAN (FR)
COURVALIN PATRICE (FR)
Application Number:
JP2003271366A
Publication Date:
March 04, 2004
Filing Date:
July 07, 2003
Export Citation:
Assignee:
PASTEUR INSTITUT (FR)
International Classes:
G01N33/50; A61K38/00; A61P31/04; C07H21/04; C07K14/195; C07K14/315; C07K16/12; C12N1/21; C12N9/00; C12N15/09; C12N15/31; C12P21/08; C12Q1/18; C12Q1/68; G01N33/15; G01N33/569; C12R1/185; (IPC1-7): C12Q1/18; A61P31/04; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Yoshio Kawaguchi