Title:
タンパク質分解調整剤およびその使用方法
Document Type and Number:
Japanese Patent JP2023517393
Kind Code:
A
Abstract:
タンパク質分解誘導キメラ分子(PROTAC)および関連疾患を治療するための医薬の製造におけるその用途。特に、式(I)で示される化合物およびその医薬的に許容される塩が開示されている。TIFF2023517393000488.tif17160
Inventors:
Shigeyoshi Rai
Peng Lei
Luo Yunfu
Xu Rain
Chestnut Toshinae
▲デン▼ 新媛
Yasushi Sei
wisdom
Guoli Zhang
Chen Akira
Peng Lei
Luo Yunfu
Xu Rain
Chestnut Toshinae
▲デン▼ 新媛
Yasushi Sei
wisdom
Guoli Zhang
Chen Akira
Application Number:
JP2022556672A
Publication Date:
April 25, 2023
Filing Date:
March 17, 2021
Export Citation:
Assignee:
Medshine Discovery Incorporated
International Classes:
C07D405/04; A61K31/444; A61K31/4545; A61K31/506; A61K31/517; A61K31/519; A61K31/551; A61P9/00; A61P31/12; A61P35/00; C07D407/14; C07D417/14; C07D471/04; C07D487/04; C07D495/14
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Other References:
JELLEY. R. A. ET AL.: "“3-Substitutedgem-cyclohexane sulfone based γ-secretase inhibitors for Alzheimer’s disease: Confo", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 16, no. 14, JPN6023042754, July 2006 (2006-07-01), pages 3839 - 3842, ISSN: 0005181030
大岡 伸通 他: "新しい低分子薬の創薬モダリティPROTAC", ファルマシア, vol. 第56巻, 第1号, JPN6023042753, 1 January 2020 (2020-01-01), pages 41 - 45, ISSN: 0005181029
大岡 伸通 他: "新しい低分子薬の創薬モダリティPROTAC", ファルマシア, vol. 第56巻, 第1号, JPN6023042753, 1 January 2020 (2020-01-01), pages 41 - 45, ISSN: 0005181029
Attorney, Agent or Firm:
Yamato Kento
Shinagawa
Futami Kamahira
Masahiro Suwon
Wu Yingyan
Shinagawa
Futami Kamahira
Masahiro Suwon
Wu Yingyan