To provide a PTP packaging device which restrains the generation of curls on a PTP packaged body as much as possible and easily carries out a post-processing.

A PTP packaging device is provided with a carrying device for carrying a resin film 10, a forming box 11 for forming a pocket 10a of the resin film during the carriage, a means of feeding a cover film 15 in a manner of covering the same set above the resin film and a sealing device 19 for pressurizing both films overlapped together while heating, and the sealing device is provided with a receiving roller 17 and a heating roller 18, and both films are pressurized and heated between both rollers. A guide roller 20 is provided on the downstream side of the sealing device, and both films integrated together are hung around the guide roller to separate imediately both films after being sealed are separated from the receiving roller and carry the films in the flat state. The films are cooled in the flat state by the arrangement to generate no curls.