Title:
球形インスリン微小粒子の肺送達
Document Type and Number:
Japanese Patent JP2010524948
Kind Code:
A
Abstract:
Compositions of spherical insulin particles having improved pulmonary application potentials and methods of forming and using these compositions are disclosed in the present application. In one clinical trial with 30 healthy male human subjects, no coughing was observed upon a single pulmonary administration of the spherical insulin particles at an insulin dose of 6.5 mg, nor during the 10-hour post dosing period.
Inventors:
Brown, Larry Earl.
McGeehan, John Kay.
Yuan Si, Chin
Rashba-Step, Julia
Scott, Terence Elle.
McGeehan, John Kay.
Yuan Si, Chin
Rashba-Step, Julia
Scott, Terence Elle.
Application Number:
JP2010504150A
Publication Date:
July 22, 2010
Filing Date:
April 02, 2008
Export Citation:
Assignee:
BAXTER INTERNATIONAL INCORP0RATED
BAXTER HEALTHCARE S.A.
BAXTER HEALTHCARE S.A.
International Classes:
A61K38/28; A61K9/50; A61P5/48
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita