Title:
PURIFICATION OF COENZYME Q
Document Type and Number:
Japanese Patent JPS56124389
Kind Code:
A
Abstract:
PURPOSE: Crude coenzyme Q is purified with silica gel chromatography using a specific developer, whereby high-purity coenzyme Q is obtained in high yield.
CONSTITUTION: Crude coenzyme Q is collected from cell bodies of microorganisms, internal organs of animals or bloody-color flesh or synthesized and dissolved in a nonpolar solvent such as n-hexane or n-pentane. Then, the solution is charged in the column of silica gel chromatography and developed by feeding a developing solvent composed of 98W90vol% methyl tert-butyl ether and 2W10vol% a nonpolar solvent. The purified coenzyme Q is eluted together with the developing solvent and collected by distilling off the solvent.
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Inventors:
URAGAMI SADAJI
TAKANO KADOYASU
TAKANO KADOYASU
Application Number:
JP2636780A
Publication Date:
September 30, 1981
Filing Date:
March 03, 1980
Export Citation:
Assignee:
MITSUBISHI GAS CHEMICAL CO
International Classes:
C12P7/66; C07C46/10; C07C50/28; (IPC1-7): C12P7/66