Title:
膵臓内分泌プレ前駆体細胞及びその子孫のDNER媒介細胞精製
Document Type and Number:
Japanese Patent JP2011518547
Kind Code:
A
Abstract:
The invention relates to a method of identifying and obtaining cells that have the potential to differentiate into pancreatic cells, having the step of contacting a cell population containing endocrine pre-progenitor cells, endocrine progenitor cells, early endocrine cells, and/or fully differentiated endocrine cells with a DNER binding agent; as well as isolating and/or expanding cells obtained by the method and compositions thereof.
Inventors:
Hald, Jacob
Madsen, Ole Dragsbake
Gladvol, Gerard
Melitzer, Georg
Madsen, Ole Dragsbake
Gladvol, Gerard
Melitzer, Georg
Application Number:
JP2011502394A
Publication Date:
June 30, 2011
Filing Date:
April 03, 2009
Export Citation:
Assignee:
Novo Nordeisk A/S
International Classes:
C12N5/077; A61K35/39; A61P1/18; A61P5/48; A61P5/50; G01N33/48; C07K16/28; C12Q1/04
Other References:
JPN6013049469; ＰＮＡＳ，Ｖｏｌ．１０４，Ｎｏ．１（２００７）ｐ．１７５-１８０
JPN6013049470; ＪＢＣ，Ｖｏｌ．２７７，Ｎｏ．２８（２００２）ｐ．２５４００-２５４０７
JPN6013049472; ＢＭＣ Ｄｅｖ．Ｂｉｏｌ．，Ｖｏｌ．７，Ｎｏ．６３（２００７）ｐ．１-１３
JPN6013049470; ＪＢＣ，Ｖｏｌ．２７７，Ｎｏ．２８（２００２）ｐ．２５４００-２５４０７
JPN6013049472; ＢＭＣ Ｄｅｖ．Ｂｉｏｌ．，Ｖｏｌ．７，Ｎｏ．６３（２００７）ｐ．１-１３
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori