Title:
ピラジン誘導体およびその医薬的使用
Document Type and Number:
Japanese Patent JP4650419
Kind Code:
B2
Abstract:
A pyrazine derivative of the following formula (I): or a salt thereof. The pyrazine compound (I) and a salt thereof of the present invention are adenosine antagonists and are useful for the prevention and/or treatment of depression, dementia (e.g. Alzheimer's disease, cerebrovascular dementia, dementia accompanying Parkinson's disease, etc.), Parkinson's disease, anxiety, pain, cerebrovascular disease (e.g. stroke, etc.), heart failure and the like.
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Inventors:
Satoshi Yokanishi
Aoki Satoshi
Matsushima Yuji
Akabane Atsushi
Aoki Satoshi
Matsushima Yuji
Akabane Atsushi
Application Number:
JP2006519017A
Publication Date:
March 16, 2011
Filing Date:
October 25, 2004
Export Citation:
Assignee:
Astellas Pharma Inc.
International Classes:
C07D401/04; A61K31/4965; A61K31/497; A61P1/04; A61P1/10; A61P1/18; A61P3/04; A61P3/10; A61P7/02; A61P7/06; A61P9/00; A61P9/06; A61P9/10; A61P9/12; A61P11/00; A61P13/12; A61P19/06; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P29/00; A61P37/02; A61P37/06; A61P43/00; C07D401/14; C07D405/14; C07D409/14
Domestic Patent References:
JP2002528506A | ||||
JP10067756A | ||||
JP2003523380A |
Foreign References:
WO2002014282A1 | ||||
WO2003035639A1 | ||||
WO2001060806A1 | ||||
WO2003045924A1 | ||||
WO2004018437A1 |
Other References:
C. G. WERMUTH 編,長瀬博 監訳,最新 創薬化学 上巻,株式会社テクノミック発行,1998年 8月15日,第1版,第240-248頁
Attorney, Agent or Firm:
Morita Taku
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke