Title:
PYRAZOLE COMPOUND AND ITS PRODUCTION
Document Type and Number:
Japanese Patent JP2000086637
Kind Code:
A
Abstract:
To profitably obtain a pyrazole compound useful as an intermediate for producing physiologically active substances such as medicines and agrochemicals by reacting a specific trifluoroacetic acid derivative with propionitrile.
A trifluoroacetic acid derivative of the formula CF3COY [Y is a halogen, OCOCF3 or OR (R is a 1-4C alkyl)] with propionitrile of the formula: CH3CH2CN in the presence of potassium t-butoxide as a base to obtain 3-oxo-4,4,4-trifluoro-2-methylbutanenitrile of the formula. The reaction is preferably carried out in an inert solvent such as benzene usually at a reaction temperature of -30 to 150°C.
Inventors:
MURAKAMI HIROSHI
MIYAJI RIKA
TANAKA NORIO
MIYAJI RIKA
TANAKA NORIO
Application Number:
JP25710698A
Publication Date:
March 28, 2000
Filing Date:
September 10, 1998
Export Citation:
Assignee:
NISSAN CHEMICAL IND LTD
International Classes:
C07D231/38; C07C253/30; C07C255/17; (IPC1-7): C07D231/38; C07C253/30; C07C255/17