Title:
ピラゾロピリミジンＪＡＫ阻害剤化合物及び方法
Document Type and Number:
Japanese Patent JP6312634
Kind Code:
B2
Abstract:
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2and R3are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.
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Inventors:
Gibbons, Paul
Hanan, Emily
Liu, Wendy
Rissikatos, Joseph P.
Magnuson, Stephen Earl.
Mendoza, Rohan
Pastor, richard
Lawson, Thomas E.
Siu, Michael
Zaku, Mark Ei.
Butterfly, aye
Zhu, Bin-Yang
Hanan, Emily
Liu, Wendy
Rissikatos, Joseph P.
Magnuson, Stephen Earl.
Mendoza, Rohan
Pastor, richard
Lawson, Thomas E.
Siu, Michael
Zaku, Mark Ei.
Butterfly, aye
Zhu, Bin-Yang
Application Number:
JP2015122441A
Publication Date:
April 18, 2018
Filing Date:
June 17, 2015
Export Citation:
Assignee:
Genentech, Incorporated
International Classes:
A61P1/00; A61K31/519; A61P1/04; A61P19/02; A61P29/00
Domestic Patent References:
| JP5769261B2 | ||||
| JP5769199B2 | ||||
| JP2007516194A | ||||
| JP2011507910A |
Foreign References:
| WO2009047359A1 |
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation