Title:
抗酸化炎症モジュレーターとしてのピラゾリルおよびピリミジニル三環式エノン
Document Type and Number:
Japanese Patent JP5857068
Kind Code:
B2
Abstract:
Disclosed herein are novel antioxidant inflammation modulators, including those of the formula:wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds and compositions thereof are also provided.
Inventors:
Anderson Eric
Bolton Garry El.
Caplace bradley
Jang Shin
Lee Chitase
Rourke William H.
Bisnick melane
Bolton Garry El.
Caplace bradley
Jang Shin
Lee Chitase
Rourke William H.
Bisnick melane
Application Number:
JP2013544872A
Publication Date:
February 10, 2016
Filing Date:
December 19, 2011
Export Citation:
Assignee:
Riata Pharmaceuticals, Inc.
International Classes:
C07D231/54; A61K31/416; A61K31/4178; A61K31/4196; A61K31/422; A61K31/4245; A61K31/4439; A61K31/4738; A61K31/506; A61K31/517; A61K31/519; A61K31/5377; A61P29/00; A61P39/06; C07D239/70; C07D401/04; C07D403/04; C07D413/04; C07D417/04; C07D471/04; C07D487/04
Domestic Patent References:
| JP8208479A | ||||
| JP52065260A |
Foreign References:
| WO2009146216A1 | ||||
| US3071577 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto