Title:
ドーパミンＤ１受容体ポジティブ調節因子としてのピラゾテトラヒドロイソキノリン誘導体
Document Type and Number:
Japanese Patent JP7083916
Kind Code:
B2
Abstract:
The invention provides certain (phenyl)-(pyrazol)-3,4-dihydroisoquinolin-2(1H)- yl)ethan-1-one compounds of formula I as D1 positive allosteric modulators (PAMs), and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula I, or a pharmaceutically acceptable salt thereof, to treat certain symptoms of Parkinson's disease, schizophrenia, ADHD or Alzheimer's disease.
Inventors:
David Andrew Coates
Junrian Hao
Daryl Wayne Hilliard
Junrian Hao
Daryl Wayne Hilliard
Application Number:
JP2020557950A
Publication Date:
June 13, 2022
Filing Date:
April 17, 2019
Export Citation:
Assignee:
Eli Lilly and Company
International Classes:
C07D401/04; A61K31/4725; A61P25/16; A61P25/28; A61P43/00; C07D405/14
Domestic Patent References:
| JP2017530185A | ||||
| JP2016520127A |
Foreign References:
| WO2017070068A1 |
Attorney, Agent or Firm:
Yamato Kento
Shinagawa
Wu Yingyan
Shinagawa
Wu Yingyan
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