Pyridine and a pyrazine derivative - Merck Patent Gesellschaft mit beschraenkter Haftung

Title:

Pyridine and a pyrazine derivative

Document Type and Number:

Japanese Patent JP6054954

Kind Code:

B2

Abstract:

Compounds of the formula (I) in which R, R1 and X have the meanings indicated in claim 1, are inhibitors of TBK1 and IKKε and can be employed, inter alia, for the treatment of cancer and inflammatory diseases

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Inventors:

Gunther Herzemann
Hans-Michael Eggenberger
Srinivasa R. Carla

Application Number:

JP2014512837A

Publication Date:

December 27, 2016

Filing Date:

April 11, 2012

Export Citation:

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Assignee:

Merck Patent Gesellschaft mit beschraenkter Haftung

International Classes:

C07D213/82; A61K31/444; A61K31/4545; A61K31/496; A61K31/497; A61K31/501; A61K31/506; A61K31/5377; A61P9/10; A61P15/00; A61P17/06; A61P19/02; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/00; A61P31/18; A61P35/00; A61P43/00; C07D401/14; C07D405/14; C07D409/14; C07D471/04; C07D491/048

Domestic Patent References:

JP2009529041A
JP2007524682A
JP2006516124A
JP2004536110A
JP2005505515A

Foreign References:

WO2010071837A1
WO2011089416A1
WO2009122180A1
WO2010100431A1

Other References:

PAQUET DOMINIK,A ZEBRAFISH MODEL OF TAUOPATHY ALLOWS IN VIVO IMAGING OF NEURONAL CELL DEATH AND DRUG EVALUATION,JOURNAL OF CLINICAL INVESTIGATION,2009年 4月13日,V119 N5,P1382-1395

Attorney, Agent or Firm:

Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Kazumi Nakamura

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