Title:
PYRIDYLMETHYL ESTER OF SELECTED BIOLOGICALLY ACTIVE CARBOXYLIC ACID
Document Type and Number:
Japanese Patent JPS57134466
Kind Code:
A
Abstract:
Novel pharmaceutically useful derivatives of selected known bio-affecting carboxylic acids are disclosed, said derivatives having the structural formula (I) wherein R1 and R2, which can be the same or different, are each hydrogen, C1-C5 alkyl, C1-C5 alkoxy, C1-C5 alkylthio, phenyl, or substituted phenyl having one or more substituents each of which is selected from the group consisting of C1-C5 alkyl, C1-C5 alkoxy, chloro and dialkylamino wherein the alkyl portions, which can be the same or different, each have 1 to 5 carbon atoms, with the proviso that when R1 is alkoxy or alkylthio, then R2 cannot be alkoxy or alkylthio; X and X', which can be the same or different, are each hydrogen, C1-C5 alkyl, carboxy, C2-C6 alkoxycarbonyl, halo, C1-C5 alkoxy, dialkylcarbamyl wherein the alkyl portions, which can be the same or different, each have 1 to 5 carbon atoms, phenyl, or substituted phenyl the pyridyl ring is oriented such that it is attached to the portion of the molecule via a carbon-carbon bond; and R-COO- is the acyloxy residue of a monocarboxylic acid; a steroidal monocarboxylic acid; or a cephalosporin or penicillin antibiotic.
Inventors:
KENESU BII SUROON
Application Number:
JP21614881A
Publication Date:
August 19, 1982
Filing Date:
December 29, 1981
Export Citation:
Assignee:
MERCK & CO INC
International Classes:
A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/4425; A61K31/4427; A61P9/12; A61P25/04; A61P29/00; A61P31/04; C07D213/30; C07D213/89; C07D401/12; C07D499/00; C07D499/32; C07D501/20; C07J43/00; C07J71/00; (IPC1-7): A61K31/44; C07D213/30; C07D213/89; C07D401/12
Domestic Patent References:
| JPS51110039A | 1976-09-29 |
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