PYRROLE DERIVATIVE AS PHARMACEUTICAL FACTOR

Japanese Patent JP2010077166

A

To provide compounds, compositions and methods for modulating the activity of receptors.

Compounds, compositions and methods for modulating the activity of receptors are provided. In particular, the compounds and compositions are provided for modulating the activity of receptors and for the treatment, prevention or amelioration of one or more symptoms of disease or disorder directly or indirectly related to the activity of the receptors. Besides, there are provided the compounds for use in pharmaceutical compositions and methods for modulating the activity of one or more steroid intranuclear receptors. The compounds have formula (I).

CANNE BANNEN LYNNE
CHEN JEFF
DALRYMPLE LISA ESTHER
FLATT BRENTON T
FORSYTH TIMOTHY PATRICK
GU XIAO-HUI
MAC MORRISON B
MANN LARRY W
MANN GRACE
MARTIN RICHARD
MOHAN RAJU
MURPHY BRETT
NYMAN MICHAEL CHARLES
STEVENS WILLIAM C JR
WANG TIE-LIN
WANG YAN
WU JASON H

JP2010007511A

April 08, 2010

January 15, 2010

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EXELIXIS INC

C07D207/34; A61K31/40; A61K31/4025; A61K31/404; A61K31/4155; A61K31/416; A61K31/4178; A61K31/4184; A61K31/42; A61K31/428; A61K31/433; A61K31/4436; A61K31/4439; A61K31/454; A61K31/4709; A61K31/4725; A61K31/496; A61K31/5377; A61K45/00; A61P3/00; A61P3/10; A61P5/44; A61P9/00; A61P9/12; A61P13/12; A61P15/08; A61P19/08; A61P21/00; A61P25/28; A61P35/00; A61P37/04; A61P43/00; C07D401/06; C07D401/12; C07D403/04; C07D403/12; C07D405/04; C07D405/06; C07D405/12; C07D409/10; C07D409/12; C07D409/14; C07D413/12; C07D417/12

JPS63307879A	1988-12-15
JPH04145078A	1992-05-19
JP4703649B2	2011-06-15

WO1999050264A1	1999-10-07
WO2004007481A2	2004-01-22
WO2004007458A1	2004-01-22
WO2004014368A1	2004-02-19
WO2004060888A1	2004-07-22
WO2004060870A1	2004-07-22

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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