Title:
PYRROLOPYRIDINE COMPOUND USEFUL AS INHIBITOR FOR PROTEIN KINASE
Document Type and Number:
Japanese Patent JP2009179644
Kind Code:
A
Abstract:
To provide a compound useful as a protein kinase inhibitor.
Provided is a composition comprising the compound, or a composition comprising a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable vehicle thereof, an adjuvant, or a solvent. The amount of compound in the composition is an effective amount to inhibit the protein kinases originating from a biological sample or a sample from a patient, in particular the JAK family or ROCK family kinases to a measurable degree. Preferably the composition is prepared for administration to a patient in need of the composition. The composition is prepared for oral administration to the patient in need of the composition.
More Like This:
WO/2001/032658 | POLYAZANAPHTHALENE COMPOUND AND MEDICINAL USE THEREOF |
WO/2007/077490 | BICYCLIC HETEROARYL COMPOUNDS AS PDE10 INHIBITORS |
Inventors:
LEDEBOER MARK W
WANNAMAKER MARION W
FARMER LUC J
WANG TIANSHENG
PIERCE ALBERT C
MARTINEZ-BOTELLA GABRIEL
BETHIEL RANDY S
BEMIS GUY W
WANG JIAN
SALITURO FRANCESCO G
ARNOST MICHAEL J
COME JON H
GREEN JEREMY
STEWART MICHELLE
MARHEFKA CRAIG
WANNAMAKER MARION W
FARMER LUC J
WANG TIANSHENG
PIERCE ALBERT C
MARTINEZ-BOTELLA GABRIEL
BETHIEL RANDY S
BEMIS GUY W
WANG JIAN
SALITURO FRANCESCO G
ARNOST MICHAEL J
COME JON H
GREEN JEREMY
STEWART MICHELLE
MARHEFKA CRAIG
Application Number:
JP2009123635A
Publication Date:
August 13, 2009
Filing Date:
May 21, 2009
Export Citation:
Assignee:
VERTEX PHARMACEUT INC
International Classes:
C07D471/04; A61K31/437; A61K31/444; A61K31/4725; A61K31/496; A61K31/506; A61K31/517; A61K31/519; A61K31/5415; A61K31/551; A61P35/00; A61P35/02; A61P43/00; C07D519/00
Domestic Patent References:
JP2004534826A | 2004-11-18 | |||
JP2003503481A | 2003-01-28 | |||
JP2004501152A | 2004-01-15 | |||
JP2008525453A | 2008-07-17 | |||
JP2008516973A | 2008-05-22 | |||
JP2007536280A | 2007-12-13 | |||
JP2007534710A | 2007-11-29 | |||
JP2008525463A | 2008-07-17 | |||
JP2008540664A | 2008-11-20 | |||
JP2008528679A | 2008-07-31 | |||
JP2009523812A | 2009-06-25 | |||
JP2008517983A | 2008-05-29 | |||
JP2008512380A | 2008-04-24 | |||
JP2007521334A | 2007-08-02 | |||
JP2007512364A | 2007-05-17 | |||
JP2008517984A | 2008-05-29 |
Foreign References:
WO2006052568A2 | 2006-05-18 | |||
WO2001081345A1 | 2001-11-01 | |||
WO2004085425A1 | 2004-10-07 | |||
WO2005013986A1 | 2005-02-17 | |||
WO2004099205A1 | 2004-11-18 | |||
WO2003091246A1 | 2003-11-06 | |||
WO2004046124A1 | 2004-06-03 | |||
WO2004074286A1 | 2004-09-02 | |||
WO2006071548A2 | 2006-07-06 | |||
WO2006044687A2 | 2006-04-27 | |||
WO2005113494A2 | 2005-12-01 | |||
WO2005108397A1 | 2005-11-17 | |||
WO2006069080A2 | 2006-06-29 | |||
WO2006124863A2 | 2006-11-23 | |||
WO2006131835A2 | 2006-12-14 | |||
WO2007084667A2 | 2007-07-26 | |||
WO2006046023A1 | 2006-05-04 | |||
WO2006026754A2 | 2006-03-09 | |||
WO2005062795A2 | 2005-07-14 | |||
WO2005051304A2 | 2005-06-09 | |||
WO2006046024A1 | 2006-05-04 |
Other References:
JPN5008006241; THUTEWOHL,MICHAEL: SYNTHESIS N4, 2006, P629-632
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita