Title:
Quantitive analysis of joint reaction velocity based on a magnetic sensor
Document Type and Number:
Japanese Patent JP6104868
Kind Code:
B2
Abstract:
Methods for quantitatively determining a binding kinetic parameter of a molecular binding interaction are provided. Aspects of embodiments of the methods include: producing a magnetic sensor device including a magnetic sensor in contact with an assay mixture including a magnetically labeled molecule to produce a detectable molecular binding interaction; obtaining a real-time signal from the magnetic sensor; and quantitatively determining a binding kinetics parameter of the molecular binding interaction from the real-time signal. Also provided are systems and kits configured for use in the methods.
Inventors:
One, Shan, X.
Gastar, Richard, S.
Z, Lian
Han, Su Jen
Robert Wilson
Gastar, Richard, S.
Z, Lian
Han, Su Jen
Robert Wilson
Application Number:
JP2014199016A
Publication Date:
March 29, 2017
Filing Date:
September 29, 2014
Export Citation:
Assignee:
INTERNATIONAL BUSINESS MACHINES CORPORATION
International Classes:
C12Q1/68; G01N27/72
Domestic Patent References:
| JP2008546995A | ||||
| JP2008528998A | ||||
| JP2009536342A |
Foreign References:
| US20090104707 | ||||
| US20090186420 |
Attorney, Agent or Firm:
Hideno Kono
Nobuo Kono
Nobuo Kono