α-1アドレナリン作動性拮抗薬としてのキナゾリン誘導体

Title:

α-1アドレナリン作動性拮抗薬としてのキナゾリン誘導体

Document Type and Number:

Japanese Patent JP3971299

Kind Code:

B2

Abstract:

This invention relates to compounds which are generally alpha-1B adrenergic receptor antagonists and which are represented by Formula (I):wherein R', R'', R1, R2, m, n, and A are as defined in the specification, or acceptable prodrug, salt or solvate thereof. The invention further relates to pharmaceutical compositions containing such compounds, methods for their use as therapeutic agents, and methods of preparation thereof.

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Inventors:

Becker, Cyrus Kefra
Melville, Chris Richard
Pfister, Jorg Roland
Tsang, Xiao Ming

Application Number:

JP2002523466A

Publication Date:

September 05, 2007

Filing Date:

August 23, 2001

Export Citation:

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Assignee:

F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT

International Classes:

C07D401/12; A61K31/506; A61P13/02; A61P15/10; A61P25/00; A61P25/04; A61P25/18; A61P25/20; A61P43/00; C07D401/14; C07D405/14

Domestic Patent References:

JP11501668A
JP9511238A

Attorney, Agent or Firm:

Hajime Tsukuni
Fumio Shinoda

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