Title:
抗増殖剤としてのキナゾリン誘導体
Document Type and Number:
Japanese Patent JP2007506725
Kind Code:
A
Abstract:
The invention concerns quinazoline derivatives of Formula I wherein each of R1a, R1b, R2, R3 and a have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases.
Inventors:
Bernard Christoph, Barlam
Halsall, Christopher Thomas
Hennekin, Laurent Francois Andre
Halsall, Christopher Thomas
Hennekin, Laurent Francois Andre
Application Number:
JP2006527495A
Publication Date:
March 22, 2007
Filing Date:
September 22, 2004
Export Citation:
Assignee:
AstraZeneca Activrag
International Classes:
C07D401/12; A61K31/517; A61P9/10; A61P13/08; A61P17/06; A61P35/00; A61P35/02; A61P43/00; C07D401/14; C07D405/14; C07D409/14; C07D413/14
Domestic Patent References:
| JP2001500891A | 2001-01-23 | |||
| JP2002538145A | 2002-11-12 | |||
| JP2003509500A | 2003-03-11 |
Foreign References:
| WO2004006846A2 | 2004-01-22 | |||
| WO2003082290A1 | 2003-10-09 |
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Ken Matsumoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Ken Matsumoto