Title:
QUINAZOLINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
Document Type and Number:
Japanese Patent JP2003238539
Kind Code:
A
Abstract:
To obtain a pharmaceutical composition containing a quinazoline compound or its pharmaceutically acceptable salt, capable of inhibiting a VEGF effect, and therefore having a valuable characteristic of treating various disease conditions, including cancer and articular rheumatism.
The pharmaceutical composition contains the quinazoline compound of formula (I) its pharmaceutically acceptable salt. The composition is used as a medicament for treating the disease conditions relating to vasculogenesis and/or increased vasopermeability, especially for producing a decreasing effect on the vasculogenesis and/or the increased vasopermeability in a warm-blooded animal, such as a human.
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Inventors:
THOMAS ANDREW PETER
HENNEQUIN LAURENT FRANCOIS A
JOHNSTONE CRAIG
STOKES ELAINE SOPHIE ELIZABETH
LOHMANN JEAN-JACQUES MARCEL
CLAYTON EDWARD
HENNEQUIN LAURENT FRANCOIS A
JOHNSTONE CRAIG
STOKES ELAINE SOPHIE ELIZABETH
LOHMANN JEAN-JACQUES MARCEL
CLAYTON EDWARD
Application Number:
JP2003079216A
Publication Date:
August 27, 2003
Filing Date:
September 23, 1997
Export Citation:
Assignee:
ZENECA LTD
ZENECA PHARMA SA
ZENECA PHARMA SA
International Classes:
A61F13/02; A61K31/505; A61K31/517; A61K31/5377; A61K31/541; A61P3/10; A61P9/00; A61P9/10; A61P13/12; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P37/00; A61P37/02; A61F13/00; A61P43/00; C07D239/93; C07D239/94; C07D401/12; C07D403/12; C07D405/12; C07D413/12; C07D417/02; C07D417/12; A61F13/15; C07D207/00; C07D211/00; C07D239/72; C07D309/02; C07D317/08; A61K; C07D; (IPC1-7): C07D239/94; A61K31/517; A61K31/5377; A61K31/541; A61P3/10; A61P9/10; A61P13/12; A61P17/06; A61P19/02; A61P27/02; A61P29/00; A61P35/00; A61P37/02; A61P43/00; C07D401/12; C07D403/12; C07D405/12; C07D413/12
Attorney, Agent or Firm:
Shusaku Yamamoto