キナゾリノン誘導体

Japanese Patent JP2004515544

A

A quinazolinone derivatives having poly (adenosine 5'-diphaspho-ribose)polymerase (PARP) inhibotory activity represented by the formula (I), wherein R1 is optionally substituted cyclic amino groups or optionally substituted amino group, R2 is substituent, n means an integer from 0 to 4, and L is lower akkylene or lower alkenylene, or its prodrug, or their salts.

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Matsuoka Shinya
Akira Iwashita
Shunji Yamazaki
Hiroshi Miyake
Mitsuru Okubo
Ikki Uejo
Nakanishi Isao
Kenji Murano
Koji Hattori
Yoshiyuki Kido
Junya Ishida
Hirofumi Yamamoto

JP2002549648A

May 27, 2004

December 05, 2001

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Fujisawa Pharmaceutical Co., Ltd.

A61K31/517; A61K31/5377; A61K31/55; A61K31/5513; A61P1/04; A61P3/08; A61P3/10; A61P9/00; A61P9/10; A61P17/02; A61P17/16; A61P19/02; A61P19/10; A61P21/00; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/28; A61P27/02; A61P31/04; A61P31/18; A61P35/00; A61P37/00; A61P39/00; A61P39/02; A61P43/00; C07D239/88; C07D239/90; C07D401/06; C07D401/12; C07D401/14; C07D403/06; C07D403/12; C07D405/12; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D487/08; (IPC1-7): C07D239/90; A61K31/517; A61K31/5377; A61K31/55; A61K31/5513; A61P1/04; A61P3/08; A61P3/10; A61P9/00; A61P9/10; A61P17/02; A61P17/16; A61P19/02; A61P19/10; A61P21/00; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/28; A61P27/02; A61P31/04; A61P31/18; A61P35/00; A61P37/00; A61P39/00; A61P39/02; A61P43/00; C07D401/06; C07D401/12; C07D401/14; C07D403/06; C07D403/12; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D487/08

Eiji Tafushi

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