To provide a method for producing a radioactive As-containing compound and obtain a pharmaceutical composition containing the compound.
The method for producing the radioactive As-containing compound comprises (i) a process for irradiating neutron to an As-containing compound (selected from the group consisting of As2O3, As2S3, As2S2 and a combination of those) and converting As contained in the As-containing compound into a radioactive As isotope; and (ii) a process for collecting the resulted product from the process (i). The pharmaceutical composition containing a therapeutically effective amount of the radioactive As-containing compound and a pharmaceutically permissible support is prescribed to an injection formulation and used for treating tumors/cancers such as hematologically malignant tumors and solid tumors.
HUANG CHUN-YING
WU MING-SHIUAN
CHEN TE-JUNG
CHANG KWO-PING
CHO SHOJU
CHYI SHYH-YI
CHANG CHIH-HSIEN
HSU YIN-MAO
FAN KUO-HSIEN
HSU WEI-CHUAN
FU YING-KAI
KAO CHARNG-FENG
INST OF NUCLEAR ENERGY RES ROC
Kakehi Yuro
Takeshi Ohara
Kenji Saito
Jun Fujii
Hitoshi Seki
Mutsuko Nakano