Title:
ＲＩＰ１阻害剤化合物並びにそれを製造及び使用するための方法
Document Type and Number:
Japanese Patent JP7379467
Kind Code:
B2
Abstract:
Disclosed herein are kinase inhibitory compounds, such as a receptor-interacting protein-1 (RIP1) kinase inhibitor compounds, as well as pharmaceutical compositions and combinations comprising such inhibitory compounds. The disclosed compounds, pharmaceutical compositions, and/or combinations may be used to inhibit a RIP1 kinase in vivo or ex vivo, and also may treat or prevent a kinase-associated disease or condition, particularly a RIP1-associated disease or condition.
Inventors:
Dalweish, Ehab
You, Jarshin
Chen, Yang
Masuda, Esteban
Taylor, Vanessa
You, Jarshin
Chen, Yang
Masuda, Esteban
Taylor, Vanessa
Application Number:
JP2021510283A
Publication Date:
November 14, 2023
Filing Date:
May 02, 2019
Export Citation:
Assignee:
Rigel Pharmaceuticals, Incorporated
International Classes:
C07D471/10; A61K31/553; A61P3/00; A61P35/00; A61P35/02; A61P43/00; C07D413/14; C07D471/08; C07D491/08; C07D491/107; C07D498/08
Domestic Patent References:
| JP2016512488A | ||||
| JP2017524028A |
Foreign References:
| WO2017136727A2 | ||||
| WO2017004500A1 |
Attorney, Agent or Firm:
Norito Yamao
Nagatoshi Shinagawa
Wu Yingyan
Wataru Sato
Nagatoshi Shinagawa
Wu Yingyan
Wataru Sato