Title:
ＲＮＡガイド遺伝子編集及び遺伝子調節
Document Type and Number:
Japanese Patent JP7085716
Kind Code:
B2
Abstract:
Disclosed herein are Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) 9-based system related compositions and methods of using said CRISPR/Cas9-based system related compositions for altering gene expression and genome engineering. Also disclosed herein are compositions and methods of using said compositions for altering gene expression and genome engineering in muscle, such as skeletal muscle and cardiac muscle.
Inventors:
Gerbach Charles Ray
Hilton Isaac Bee
Perez Pinella Pablo
Kabaddi Amiem
Southern Platyfish Eye
Oster Auto David Gee
Black Joshua Bee
Hilton Isaac Bee
Perez Pinella Pablo
Kabaddi Amiem
Southern Platyfish Eye
Oster Auto David Gee
Black Joshua Bee
Application Number:
JP2016518017A
Publication Date:
June 17, 2022
Filing Date:
June 05, 2014
Export Citation:
Assignee:
Duke University
International Classes:
C12N15/09; A61K31/7088; A61K35/30; A61K35/33; A61K35/34; A61K35/545; A61K38/00; A61K48/00; C07K19/00; C12N5/10; C12N9/16; C12N15/85
Other References:
J.Gene Med,2011,Vol.13,pp.522-537
Nature Biotechnology,2013.March,Vol.31,No.3,pp.230-232
Journal of Human Genetics,2010,Vol.55,pp.379-388
Nature Biotechnology,2013.March,Vol.31,No.3,pp.230-232
Journal of Human Genetics,2010,Vol.55,pp.379-388
Attorney, Agent or Firm:
Shinichiro Tanaka
Yoshi Kazuhiko Ta
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Gen Tashiro
Yoshi Kazuhiko Ta
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Gen Tashiro