RADIATION DERIVATIVES OF IODINE-LABELED ESTRADIENE, MANUFACTURE, INTERMEDIATES, RESEARCHES THEREON AND USE FOR RADIATION IMMUNOLOGICAL DETERMINATION OF STEROID IN BIOLOGICAL SOLUTION

Title:

RADIATION DERIVATIVES OF IODINE-LABELED ESTRADIENE, MANUFACTURE, INTERMEDIATES, RESEARCHES THEREON AND USE FOR RADIATION IMMUNOLOGICAL DETERMINATION OF STEROID IN BIOLOGICAL SOLUTION

Document Type and Number:

Japanese Patent JPS6011499

Kind Code:

A

Abstract:

Novel radioactive estradienes labelled with tritium of the formula I wherein 3H is tritium and R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and acyl of an organic carboxylic acid of 1 to 10 carbon atoms and the study and radioimmunological determination of non-radioactive 11 beta -(4-dimethylaminophenyl)-17 alpha -(prop-1-ynyl)- DELTA 4,9-estradiene-17 beta -ol-3-one and its metabolites in biological fluids and novel intermediates.

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Inventors:

ARAN JIYUKE
JIYAN SARUMON
MISHIERU MUURAN
GAETAN TOUIE

Application Number:

JP11924084A

Publication Date:

January 21, 1985

Filing Date:

June 12, 1984

Export Citation:

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Assignee:

ROUSSEL UCLAF

International Classes:

A61K51/00; A61K51/04; C07B59/00; G01N33/53; C07J1/00; C07J9/00; C07J21/00; C07J41/00; C07J43/00; G01N33/534; G01N33/74; (IPC1-7): C07J9/00; A61K49/02; C07J43/00

Attorney, Agent or Firm:

Motohiro Kurauchi

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