Title:
放射標識されたｍＧｌｕＲ２ ＰＥＴリガンド
Document Type and Number:
Japanese Patent JP6861154
Kind Code:
B2
Abstract:
The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds.
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Inventors:
Bangur, michael, look, maria
Andre-Gill, Jose, Ignatius
Alcazar-Beca, Manuel, Jesus
Bormanns, Guy, Maurits, Earl.
Selenium, Sophie, Jeanne, Leopoldi
Bell beak, juist
Andre-Gill, Jose, Ignatius
Alcazar-Beca, Manuel, Jesus
Bormanns, Guy, Maurits, Earl.
Selenium, Sophie, Jeanne, Leopoldi
Bell beak, juist
Application Number:
JP2017529296A
Publication Date:
April 21, 2021
Filing Date:
December 02, 2015
Export Citation:
Assignee:
Janssen Pharmaceuticals N.B.
International Classes:
C07D487/04; A61K31/4985; A61P25/00; A61P25/18; A61P25/24; A61P25/28; A61P43/00
Domestic Patent References:
| JP2007507446A | ||||
| JP2013189395A |
Foreign References:
| WO2012062752A1 |
Other References:
GILFILLAN, L. et al.,MedChemComm,2013年,Vol. 4,pp. 1118-1123
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Junko Kobayashi
Ryo Hoshikawa
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Junko Kobayashi
Ryo Hoshikawa
Yasuhito Suzuki