Title:
反応条件センサー
Document Type and Number:
Japanese Patent JP2007501387
Kind Code:
A
Abstract:
A method and apparatus for detecting adverse conditions during the analysis of chemical and biological processes are disclosed. In one embodiment, the reaction conditions in a microelectrochemical reaction chamber are monitored. The reaction chamber comprises electrodes arranged to pass an electric current through reaction mixture located within the reaction chamber, thereby inducing an electrochemical reaction. A detection circuit is provided to detect and measure the electric current flowing between the electrodes. The detection circuit is arranged to generate a signal indicating whether the measured current lies inside or outside a predetermined range of values. If the measured current lies outside the expected range of values, then the reaction conditions are adverse. A single pair of electrodes may perform a dual function of both inducing the electrochemical reaction and allowing the current flowing through the mixture to be measured. In another embodiment, electrodes are used to monitor the conditions in a chamber for detecting the presence of analytes using the combined techniques of surface enhanced Raman scattering and surface plasmon resonance.
Inventors:
Allen, Brian Philip
Gilbert, richard
Zhou, Xiao Feng
Gilbert, richard
Zhou, Xiao Feng
Application Number:
JP2006522387A
Publication Date:
January 25, 2007
Filing Date:
July 19, 2004
Export Citation:
Assignee:
E2V Biosensors Limited
International Classes:
G01N27/416; B01J19/00; B01L3/00; C12M1/34; C12Q1/00; G01N21/65; G01N27/28; G01N33/487; G01N21/27; G01N37/00
Domestic Patent References:
| JP2002542461A | 2002-12-10 | |||
| JPH08502589A | 1996-03-19 | |||
| JPH05502727A | 1993-05-13 | |||
| JPS5797434A | 1982-06-17 | |||
| JPS5797436A | 1982-06-17 | |||
| JP2004245836A | 2004-09-02 | |||
| JPH09257578A | 1997-10-03 | |||
| JPH05195312A | 1993-08-03 | |||
| JPS60131450A | 1985-07-13 | |||
| JP2000275254A | 2000-10-06 | |||
| JP2003004691A | 2003-01-08 |
Foreign References:
| WO2000022158A1 | 2000-04-20 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura