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Title:
REAGENTS AND METHODS FOR PREPARING LPS ANTAGONIST B1287 AND STEREOISOMERS THEREOF
Document Type and Number:
Japanese Patent JP2013136625
Kind Code:
A
Abstract:

To provide methods for preparing LPS antagonist lipodisaccharide B1287 and stereoisomers thereof, which compounds are useful in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia and various forms of septic shock.

This invention relates to: a compound represented below; useful synthetic intermediates; and a purification process including separation by chromatography and treatment using a base.


Inventors:
FAN RULIN
Application Number:
JP2013046284A
Publication Date:
July 11, 2013
Filing Date:
March 08, 2013
Export Citation:
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Assignee:
EISAI R&D MAN CO LTD
International Classes:
C07H15/04; A61P31/04; C07H3/04; C07H9/04; C07H15/12
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita