Title:
RECOGNITION MOLECULE INTERACTING SPECIFICALLY WITH ACTIVE SITE OR CLEFT OF TARGET MOLECULE
Document Type and Number:
Japanese Patent JP2009040780
Kind Code:
A
Abstract:
To find a recognition molecule having the ability to interact with the active site or cleft of a target molecule.
The recognition molecule has an exposed loop structure which extends from a basic recognition unit. The loop structure is, for example, the CDR3 of a camelid species heavy chain antibody having a binding specificity to the active site or cleft of a target molecule or a derived version of such a CDR3. The basic recognition unit is, for example, formed by an antibody type-structure having binding affinity for the target molecule.
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Inventors:
MUYLDERMANS SERGE
WYNS LODE
WYNS LODE
Application Number:
JP2008195891A
Publication Date:
February 26, 2009
Filing Date:
July 30, 2008
Export Citation:
Assignee:
VLAAMS INTERUNIV INST BIOTECH
International Classes:
A61K45/00; G01N33/531; A61K38/55; A61K39/00; A61K39/395; A61P31/04; A61P31/12; A61P39/02; A61P43/00; C07K16/00; C07K16/12; C07K16/18; C07K16/40; C12N15/09; C12N15/10; C12N15/62; C12P21/02; G01N33/15; G01N33/50; A61K38/00; C12R1/19
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta
Samejima Mutsumi
Masahiro Nitta
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