Title:
RECOMBINANT EXPRESSION VECTOR EXPRESSING HUMAN UROKINASE AND TRANSFORMED CELL
Document Type and Number:
Japanese Patent JP2584192
Kind Code:
B2
Abstract:
PURPOSE: To obtain a recombinant human urokinase in various forms including a form different from a native form in high purity.
CONSTITUTION: A human urokinase structural gene is cloned by using the whole mRNA of a Detroit 562 cell and utilized to produce a human urokinase protein in various forms such as of a material of a high-molecular weight form, a material of a low-molecular weight form or a preform material of a high- molecular weight form and respective single chain and two chain materials in a purity without substantially containing impurities.
Inventors:
HERUBERUTO RUISU HINKERU
UIRIAMU EBANSU HOMUZU
GOODON ARAN UIHAA
UIRIAMU EBANSU HOMUZU
GOODON ARAN UIHAA
Application Number:
JP1431094A
Publication Date:
February 19, 1997
Filing Date:
February 08, 1994
Export Citation:
Assignee:
GENENTECH INC
International Classes:
A61K35/74; A61K38/00; A61K38/46; A61P7/02; A61P9/10; C07H21/04; A61K38/48; C12N1/19; C12N1/20; C12N1/21; C12N5/00; C12N5/10; C12N9/72; C12N15/00; C12N15/09; C12N15/58; C12R1/19; C12R1/865; C12R1/91; C12N; (IPC1-7): C12N15/09; C12N1/19; C12N1/21; C12N5/10
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)