REDOX MOLECULE-DETECTING METHOD AND ASSAY BY EMISSION OF LIGHT

Japanese Patent JP2015083549

A

PROBLEM TO BE SOLVED: To provide a detecting method and assay of vitamin C by emission of light which has increased response speed and higher sensitivity than conventional method in bioimaging which can elucidate the behavior of vitamin C in vivo (such as inside a cell), to provide a novel redox-responsive fluorescent probe, and to provide a redox molecule-detecting method and assay using the same for the purpose.SOLUTION: The invention provides a fluorescent probe consisting of a complex comprising albumin, particularly biological molecules, such as bovine serum albumin, and a phthalocyaninato silicon complex having nitroxide radical as an axial ligand; and a detecting method and assay of vitamin C in or ex vivo using the same.

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ISHII KAZUYUKI
YOKOI TAKANORI

JP2013222318A

April 30, 2015

October 25, 2013

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FOUND PROMOTION IND SCIENCE

A61K49/00; A61K47/42; C09K11/06; G01N21/78

Patent business corporation Tsukuni
Hajime Tsukuni
Yasuo Yanagibashi
Satoko Ito
Keiko Ozawa
Yoko Tanaka

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