Title:
低減した摂食-絶食効果を伴うフィブラート-スタチンの組合わせ
Document Type and Number:
Japanese Patent JP2004523552
Kind Code:
A
Abstract:
This invention discloses an orally administered pharmaceutical composition for the treatment of elevated levels of cholesterol and related conditions comprising a statin and fenofibrate in the form of microparticles of solid fenofibrate that are stabilized by phospholipid as a surface active substance, wherein a therapeutically effective amount of the composition provides the statin and a quantity of fenofibrate to a fasted human patient that is greater than 80% of the quantity of fenofibrate provided by the same amount of the composition when administered to the same patient who has been fed a high fat meal.
Inventors:
Givarucci, Pol-Henry
Pariku, indus
Snow, Donkey A
Pariku, indus
Snow, Donkey A
Application Number:
JP2002567269A
Publication Date:
August 05, 2004
Filing Date:
April 20, 2001
Export Citation:
Assignee:
Skypharma Canada Inc.
International Classes:
A61K9/14; A61K9/16; A61K9/20; A61K9/26; A61K9/32; A61K9/48; A61K31/216; A61K31/22; A61K31/365; A61K31/366; A61K31/40; A61K31/404; A61K31/405; A61K31/44; A61K31/4418; A61K31/505; A61K31/66; A61K38/00; A61K45/06; A61K47/24; A61K47/26; A61P3/00; A61P3/06; (IPC1-7): A61K38/00; A61K9/14; A61K9/20; A61K9/32; A61K9/48; A61K31/216; A61K31/22; A61K31/366; A61K31/40; A61K31/404; A61K31/4418; A61K31/505; A61K47/24; A61K47/26; A61P3/00; A61P3/06
Foreign References:
| WO2000037078A1 | 2000-06-29 | |||
| WO2000030616A1 | 2000-06-02 |
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroaki Noya
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroaki Noya