Title:
還元酵素及びその利用
Document Type and Number:
Japanese Patent JP4745762
Kind Code:
B2
Abstract:
To provide a reductive enzyme suitable for the method of industrial production of an optically active alcohol compound from a ketone or an aldehyde.
This modified reductive enzyme of a wild type reductive enzyme obtained from bacteria belonging to the genus Rhodococcus is prepared by a gene engineering way and characterized by having amino acid substitutions at least in 6 positions of 12th, 42nd, 67th, 125th, 173rd, 327th in its sequence consisting of the 336 amino acids.
COPYRIGHT: (C)2007,JPO&INPIT
Inventors:
Shinya Ito
Makino Shoji
Tohru Ouri
Makino Shoji
Tohru Ouri
Application Number:
JP2005254459A
Publication Date:
August 10, 2011
Filing Date:
September 02, 2005
Export Citation:
Assignee:
Sumitomo Chemical Co., Ltd.
Shinya Ito
Shinya Ito
International Classes:
C12N15/09; C12N1/21; C12N9/04; C12P7/02
Domestic Patent References:
| JP2004350625A |
Other References:
Appl. Environ. Mirobiol., 2005.08, Vol.71, No.8, p.4713-4720
Biosci. Biotechnol. Biochem., 1999, Vol.63, No.12, p.2216-2218
Biosci. Biotechnol. Biochem., 1999, Vol.63, No.12, p.2216-2218
Attorney, Agent or Firm:
Toru Nakayama