Title:
BETA-CASEIN A2 AND REDUCING OR PREVENTING SYMPTOMS OF LACTOSE INTOLERANCE
Document Type and Number:
Japanese Patent JP2018203753
Kind Code:
A
Abstract:
To provide compositions and methods for reducing symptoms of lactose intolerance such as abdominal bloating and cramps, flatulence, diarrhea, nausea, rumbling stomach and vomiting.SOLUTION: The invention provides a method for reducing symptoms of lactose intolerance by administering a composition comprising at least 75 wt.% a beta casein variant having proline at position 67 of beta casein amino acid sequence so as to prevent or minimize changes in genes such as AKR1C1, AKR1C2 and OOKBR, those regulating the activity and levels of enzymes involved in digestive processes and intestinal functions. Preferably, the beta casein comprises at least 75 wt.% beta casein A2.SELECTED DRAWING: Figure 1
Inventors:
ANDREW JOHN CLARKE
Application Number:
JP2018153472A
Publication Date:
December 27, 2018
Filing Date:
August 17, 2018
Export Citation:
Assignee:
A2 MILK COMPANY LTD
International Classes:
A61K38/16; A23C9/00; A23C9/13; A23C13/14; A23C15/12; A23C19/06; A23G9/40; A23L33/19; A61K35/20; A61P1/00; A61P1/06; A61P1/08; A61P1/12; A61P43/00
Attorney, Agent or Firm:
Shinjiro Ono
Osamu Yamamoto
Osamu Yamamoto