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Title:
Refining of the antibody which uses false moving bed chromatography
Document Type and Number:
Japanese Patent JP6010030
Kind Code:
B2
Abstract:
The present invention relates to compositions and methods for the chromatographic purification of antibodies, such as monoclonal antibodies, employing improved simulated moving bed separation strategies and, in certain embodiments, Raman spectroscopy.

Inventors:
Lau, Siu-Man Kelvin
Don, Diane
Rou, Stephen
Application Number:
JP2013529353A
Publication Date:
October 19, 2016
Filing Date:
September 16, 2011
Export Citation:
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Assignee:
AbbVie Incorporated
International Classes:
C07K1/22; C07K16/00; C12P21/00; C12P21/08
Domestic Patent References:
JP2006507249A
JP2007525662A
JP2005306827A
Other References:
Process Control and Quality,1994年,Vol.6,p.133-140
ANALUSIS MAGAZINE,1994年,Vol.22,No.10,M32-M34
VDI-BERICHTE,2002年,Vol.1667,p.81-85
Journal of Raman Spectroscopy,2005年,Vol.36,p.307-319
Attorney, Agent or Firm:
Kawaguchi International Patent Office