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Title:
Refining of the precursor compound by crystallization
Document Type and Number:
Japanese Patent JP6240507
Kind Code:
B2
Abstract:
The invention relates to a process for preparation of radiopharmaceutical precursors, and in particular protected amino acid derivatives which are used as precursors for production of radiolabelled amino acids for use in in vivo imaging procedures such as positron emission tomography (PET). Particularly, the invention relates to a process for preparation of a precursor useful in the preparation of the [18F]-1 -amino-3-fluorocyclobutanecarboxylic acid ([18F] FACBC) PET tracer.

Inventors:
Nilsen, Anne
Nilsen, Sondre
Application Number:
JP2013545271A
Publication Date:
November 29, 2017
Filing Date:
December 19, 2011
Export Citation:
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Assignee:
GE HEALTHCARE LIMITED
International Classes:
C07C303/28; C07B59/00; C07C227/20; C07C229/48; C07C309/06
Domestic Patent References:
JP60199868A
JP1077257A
JP2006510706A
Foreign References:
WO2008078589A1
WO2007132689A1
WO2007063824A1
WO2010013666A1
WO2009078396A1
Attorney, Agent or Firm:
Arakawa Satoshi
Hirokazu Ogura
Toshihisa Kurokawa
Takuto Tanaka