REMODELING AND GLYCOCONJUGATION OF PEPTIDES

Japanese Patent JP2012143250

A

To provide more effective granulocyte colony stimulating factor (G-CSF).

A method for covalently bonding a modifying group having a glycosyl group to a G-CSF factor and a covalent conjugate obtained by the method are provided.

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DE FREES SHAWN
ZOPF DAVID
BAYER ROBERT
BOWE CARYN
HAKES DAVID
CHEN XI

JP2012106130A

August 02, 2012

May 07, 2012

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NOVO NORDISK AS

C12N15/09; C12P21/02; A61K38/00; A61K38/21; A61K38/22; A61K38/27; A61K38/28; A61K38/46; A61K38/48; A61K38/55; A61K39/395; A61K47/48; A61P1/16; A61P3/10; A61P5/10; A61P7/04; A61P7/06; A61P19/10; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P35/00; A61P37/04; A61P37/08; A61P43/00; C07H19/10; C07K1/00; C07K1/107; C07K1/13; C07K2/00; C07K9/00; C07K14/00; C07K14/435; C07K14/47; C07K14/505; C07K14/535; C07K14/55; C07K14/56; C07K14/565; C07K14/57; C07K14/59; C07K14/61; C07K14/62; C07K14/705; C07K14/715; C07K14/755; C07K14/81; C07K16/08; C07K16/18; C07K16/24; C07K16/28; C12N9/16; C12N9/22; C12N9/26; C12N9/42; C12N9/64; C12N9/72; C12P19/26; C12P21/00; C12P21/06; C12P21/08

JP2005328782A	2005-12-02
JPH03503759A	1991-08-22

JPN6008022592; Ｂｉｏｍａｔｅｒｉａｌｓ．　２００１　Ｍａｒ，　Ｖｏｌ．２２，　Ｎｏ．５，　ｐ．４０５-４１７
JPN6008066717; Ｇｌｙｃｏｂｉｏｌｏｇｙ．　２００６，　Ｖｏｌ．１６，　Ｎｏ．９，　ｐ．８３３-８４３
JPN6011068303; 日本生化学会　編: 新生化学実験講座３　糖質Ｉ　糖タンパク質（上） 第１版, 19900521, ｐ．３４０, 東京化学同人
JPN6013037691; Ｂｉｏｃｈｅｍｉｓｔｒｙ．　２００１　Ｊｕｌ，　Ｖｏｌ．４０，　Ｎｏ．３０，　ｐ．８８６８-８８７６

Yoshiyuki Inaba
Toshifumi Onuki

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