Title:
体外治療による毒性因子の除去
Document Type and Number:
Japanese Patent JP2013518687
Kind Code:
A
Abstract:
A method to remove virulence factors from infected blood by passing the blood through a surface cartridge with immobilized carbohydrates, such as heparin, wherein the virulence factors are toxins released from pathogens such as B. anthracis, S. aureus, and P. aeruginosa.
Inventors:
Maclea, keith
Ward, robert es
Ward, robert es
Application Number:
JP2012552160A
Publication Date:
May 23, 2013
Filing Date:
February 09, 2011
Export Citation:
Assignee:
Xterra Medical LLC
International Classes:
A61L31/00; A61M1/36
Domestic Patent References:
| JP2000334037A | 2000-12-05 | |||
| JP2009521413A | 2009-06-04 | |||
| JP2000334037A | 2000-12-05 |
Foreign References:
| WO2008157570A2 | 2008-12-24 |
Other References:
JPN6014003785; Ｔｈｏｍａｓ，Ｒ． ｅｔ ａｌ: 'Ｃｏｍｍｏｎ ｏｌｉｇｏｓａｃｃｈａｒｉｄｅ ｍｏｉｅｔｉｅｓ ｉｎｈｉｂｉｔ ｔｈｅ ａｄｈｅｒｅｎｃｅ ｏｆ ｔｙｐｉｃａｌ ａｎｄ ａｔｙｐｉｃａｌ ｒｅｓｐｉｒａｔｏｒｙ ｐａｔｈｏｇｅｎｓ' Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃａｌ Ｍｉｃｒｏｂｉｏｌｏｇｙ Ｖｏｌ．５３， Ｎｏ．９, 2004, ｐ．８３３-８４０
JPN6014003787; Ｐｏｐｏｖａ，Ｔ．Ｇ． ｅｔ ａｌ: 'Ａｃｃｅｌｅｒａｔｉｏｎ ｏｆ ｅｐｉｔｈｅｌｉａｌ ｃｅｌｌ ｓｙｎｄｅｃａｎ-１ ｓｈｅｄｄｉｎｇ ｂｙ ａｎｔｈｒａｘ ｈｅｍｏｌｙｔｉｃ ｖｉｒｕｌｅｎｃｅ ｆａｃｔｏｒｓ' ＢＭＣ Ｍｉｃｒｏｂｉｏｌｏｇｙ Ｖｏｌ．６：８, 2006, ｐ．１-１６
JPN6014046737; Ｐｙｏｎｇ Ｗｏｏ Ｐａｒｋ ｅｔ ａｌ．: 'Ａｃｔｉｖａｔｉｏｎ ｏｆ Ｓｙｎｄｅｃａｎ-１ Ｅｃｔｏｄｏｍａｉｎ Ｓｈｅｄｄｉｎｇ ｂｙ Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ alpha-Ｔｏｘｉｎ ａｎｄ beta-Ｔｏｘｉｎ' ＴＨＥ ＪＯＵＲＮＡＬ ＯＦ ＢＩＯＬＯＧＩＣＡＬ ＣＨＥＭＩＳＴＲＹ Ｖｏｌ．２７９, 20031022, Ｎｏ．１
JPN6014003787; Ｐｏｐｏｖａ，Ｔ．Ｇ． ｅｔ ａｌ: 'Ａｃｃｅｌｅｒａｔｉｏｎ ｏｆ ｅｐｉｔｈｅｌｉａｌ ｃｅｌｌ ｓｙｎｄｅｃａｎ-１ ｓｈｅｄｄｉｎｇ ｂｙ ａｎｔｈｒａｘ ｈｅｍｏｌｙｔｉｃ ｖｉｒｕｌｅｎｃｅ ｆａｃｔｏｒｓ' ＢＭＣ Ｍｉｃｒｏｂｉｏｌｏｇｙ Ｖｏｌ．６：８, 2006, ｐ．１-１６
JPN6014046737; Ｐｙｏｎｇ Ｗｏｏ Ｐａｒｋ ｅｔ ａｌ．: 'Ａｃｔｉｖａｔｉｏｎ ｏｆ Ｓｙｎｄｅｃａｎ-１ Ｅｃｔｏｄｏｍａｉｎ Ｓｈｅｄｄｉｎｇ ｂｙ Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ ａｕｒｅｕｓ alpha-Ｔｏｘｉｎ ａｎｄ beta-Ｔｏｘｉｎ' ＴＨＥ ＪＯＵＲＮＡＬ ＯＦ ＢＩＯＬＯＧＩＣＡＬ ＣＨＥＭＩＳＴＲＹ Ｖｏｌ．２７９, 20031022, Ｎｏ．１
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Go Kajita
Yasushi Kobayashi
Hiroyuki Tomita
Osamu Hoshino
Go Kajita