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Title:
光学活性ジアザスピロ[4.5]デカン誘導体の分割
Document Type and Number:
Japanese Patent JP7229917
Kind Code:
B2
Abstract:
The present disclosure is directed to intermediates and salts thereof useful for the preparation of spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1). Processes of preparing the intermediates, salts, and TPH inhibitors are also provided.

Inventors:
De Lombard, Stephan
Goldberg, Daniel Earl.
Application Number:
JP2019525887A
Publication Date:
February 28, 2023
Filing Date:
November 09, 2017
Export Citation:
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Assignee:
ALTAVANT SCIENCES GmbH
International Classes:
C07H9/04; C07D471/10
Domestic Patent References:
JP2004002470A
JP2003502325A
JP50039652B1
Foreign References:
WO2010147094A1
Other References:
BATHORI,Nikoletta B.,ChemComm,2015年,51,5664-5667
新井和孝,有機合成化学,1986年,44(6),486-498
YAMADA,Shigeki,J.Org.Chem.,1983年,48(6),843-846
Attorney, Agent or Firm:
Masatoshi Kurata
Nobuhisa Nogawa
Tadashi Inoue
Shigeru Iino
Naoki Kono
Sanae Kaneko