Title:
Ring-reduced morphinan and its use
Document Type and Number:
Japanese Patent JP6353543
Kind Code:
B2
Abstract:
The application is directed to compounds of Formula (I) or (IA) and pharmaceutically acceptable salts and solvates thereof, wherein R1 R2, R3 and G are defined as set forth in the specification. The invention is also directed to use of compounds of Formula (I) or( IA), and the pharmaceutically acceptable salts and solvates thereof, to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
Inventors:
Rockman Jeffery
Tafesse, Lakey
Tafesse, Lakey
Application Number:
JP2016542667A
Publication Date:
July 04, 2018
Filing Date:
December 19, 2014
Export Citation:
Assignee:
PURDUE PHARMA L.P.
International Classes:
A61K31/4748; C07D221/22; A61K31/496; A61K31/5377; A61K31/541; A61P1/10; A61P1/12; A61P25/02; A61P25/04; A61P25/30; A61P25/32; A61P25/36; A61P29/00; A61P43/00; C07D401/06; C07D401/12; C07D413/12
Domestic Patent References:
| JP2009545629A |
Foreign References:
| WO1995003308A1 | ||||
| WO2013167963A1 | ||||
| GB992796B |
Other References:
TAKEDA, M., et. al.,Synthesis of N-Substituted C-Normorphinans and Their Pharmacological Properties,Chem. Pharm. Bull,1992年,Vol. 40, No.5,p.1186-1190
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki
Norio Omori
Kyoei Sugiyama
Yasuhito Suzuki
Previous Patent: The filtering method of a video advertisement, a device, and equipment
Next Patent: JPS6353544
Next Patent: JPS6353544