Title:
S1P受容体調節化合物およびその使用
Document Type and Number:
Japanese Patent JP5191497
Kind Code:
B2
Abstract:
The present invention relates to compounds of the general formula (I) that have activity as SIP receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate SIP receptor activity. The compounds may be used as immunomodulators, e.g., for treating or preventing diseases such as autoimmune and related immune disorders including systemic lupus erythematosus, inflammatory bowel diseases such as Crohn's disease and ulcerative colitis, type I diabetes, uveitis, psoriasis, myasthenia gravis, rheumatoid arthritis, non-glomerular nephrosis, hepatitis, Behcet's disease, glomerulonephritis, chronic thrombocytopenic purpura, hemolytic anemia, hepatitis and Wegner's granuloma; and for treating other conditions.
Inventors:
Saha, Assis
You, Shan Wai.
Lovera, mercedes
Lin, Chian
Sherac, Srinivasa Earl.
Becker, Oren
Marantz, Yale
Shutsu, Niri
Bari, Roland
Say, Victor Jay.
Golden, jennifer
Bran Alan, Ranman
Neira, Susana
Macquarie, Dilara
Obach, Pini
Shaladendou, Anurag
Penland, Robert Sea.
Ganon, Kimberley
Shakam, Sharon
Neumann, Sylvia
Chan, Chaoda
You, Shan Wai.
Lovera, mercedes
Lin, Chian
Sherac, Srinivasa Earl.
Becker, Oren
Marantz, Yale
Shutsu, Niri
Bari, Roland
Say, Victor Jay.
Golden, jennifer
Bran Alan, Ranman
Neira, Susana
Macquarie, Dilara
Obach, Pini
Shaladendou, Anurag
Penland, Robert Sea.
Ganon, Kimberley
Shakam, Sharon
Neumann, Sylvia
Chan, Chaoda
Application Number:
JP2009554496A
Publication Date:
May 08, 2013
Filing Date:
March 21, 2007
Export Citation:
Assignee:
Epics Pharmaceuticals, Inc.
International Classes:
C07D403/10; A61K31/41; A61K31/416; A61K31/4184; A61K31/423; A61K31/428; A61K31/4355; A61K31/437; A61P1/00; A61P1/04; A61P1/16; A61P3/10; A61P7/06; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P21/04; A61P25/00; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07D413/10; C07D417/10; C07D471/04; C07D491/048
Domestic Patent References:
| JP7252254A | ||||
| JP10204059A |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita