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Title:
SALT OR CO-CRYSTAL OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL
Document Type and Number:
Japanese Patent JP2016188218
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a form allowing controlled-release of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol compound and suitable for administration for the medical treatment of sharp pain.SOLUTION: The compound is a salt or co-crystal of (a constituent a) 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol and (a constituent b1) at least one kind of acid selected from embonic acid, dibenzoyl tartaric acid, etc., or (a constituent b2) at least one kind of acid selected from nicotinic acid, etc., (where, the salt or co-crystal of the constituent (a) and the constituent (b2) exists in a crystalline form and/or an amorphous form).SELECTED DRAWING: None

Inventors:
GRUSS MICHAEL
MAGDA KRASZEWSKI
Application Number:
JP2016098733A
Publication Date:
November 04, 2016
Filing Date:
May 17, 2016
Export Citation:
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Assignee:
GRUENENTHAL GMBH
International Classes:
C07C215/54; A61K31/137; A61P25/04; A61P25/06; C07C55/20; C07C65/11; C07C69/78
Domestic Patent References:
JPH0899939A1996-04-16
JP2004527491A2004-09-09
JP5968884B22016-08-10
Other References:
C.G.WERMUTH編, 「最新 創薬化学 下巻」, vol. 347〜365頁, JPN6014029314, 1999, ISSN: 0003512585
Attorney, Agent or Firm:
Mitsufumi Esaki
Blacksmith
Katsunori Uenishi