PURPOSE: A salt-resistant catalase useful for food processing such as decomposition and removal of remaining H2O2 attached to herring roe, clinical examination, etc., having high relative activity in a salt-containing aqueous solution.

CONSTITUTION: A mold such as Hansenula philodendra, etc., is cultivated in a medium containing yeast essence, KH2PO4, etc., and the prepared mold is extracted and purified to give a heat-resistant catalase showing physical properties such as 200,000W260,000 molecular weight, salt resistance showing ≥50% relative activity in an aqueous solution having ≥7W/V% salt concentration, 30W50°C optimum temperature, pH stability of pH 6W9, heat resistance of 50W60°C, etc. Then herring roe with remaining attached H2O2 is added to an aqueous solution which contains about 5U/ml of the salt-resistant catalase and ≥7W/V% salt to decompose and to remove H2O2.