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Patent Searching and Data


Title:
SALTS OF HIV INHIBITOR COMPOUNDS
Document Type and Number:
Japanese Patent JP2014122235
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide salts of HIV inhibitor compounds.SOLUTION: The invention relates to salts of antiviral compounds, a composition containing such salts, a treatment method containing administration of such salts, a process and an intermediate useful for manufacturing such salts. The invention provides stable salts of ethyl N-[(S)-({[(2R,5R)-5-(6-amino-9H-purine-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]oxy}methyl)phenoxyphosphinoyl]-L-alaninate which is physically more stable, easier to isolate and formulate than a free base type of the compound.

Inventors:
GRAETZ BENJAMIN R
RICHARD P POLNIASZEK
Application Number:
JP2014054797A
Publication Date:
July 03, 2014
Filing Date:
March 18, 2014
Export Citation:
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Assignee:
GILEAD SCIENCES INC
International Classes:
C07F9/6558; A61K31/664; A61K45/00; A61P31/18; C07C55/08; C07C55/10; C07C59/265
Attorney, Agent or Firm:
山本 秀策
森下 夏樹