Title:
Scaffold protein based on the fibronectin which has the improved stability
Document Type and Number:
Japanese Patent JP6023703
Kind Code:
B2
Abstract:
The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.
Inventors:
Ray Camphausen
John O'Loughlin
Bernice Yang
Jean Iphone
John O'Loughlin
Bernice Yang
Jean Iphone
Application Number:
JP2013512226A
Publication Date:
November 09, 2016
Filing Date:
May 26, 2011
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C12N15/09; A61K31/7088; A61K38/00; A61P35/00; C07K14/78; C07K19/00
Domestic Patent References:
| JP2007516707A | ||||
| JP2010510315A | ||||
| JP2013531613A | ||||
| JP2010527607A | ||||
| JP2011522517A |
Foreign References:
| WO2009142773A1 |
Other References:
Duan et al,Biochemistry,2007年,Vol.46,p.12656-12664
Lu et al,Journal of Biological Chemistry,2004年 1月23日,Vol.279, No.4,p.2856-2865
Duan et al,Biochemistry,2007年,Vol. 46,pp.12656-12664
Lu et al,Journal of Biological Chemistry,2004年 1月23日,Vol. 279, No. 4,pp.2856-2865
Lu et al,Journal of Biological Chemistry,2004年 1月23日,Vol.279, No.4,p.2856-2865
Duan et al,Biochemistry,2007年,Vol. 46,pp.12656-12664
Lu et al,Journal of Biological Chemistry,2004年 1月23日,Vol. 279, No. 4,pp.2856-2865
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita
Fumio Inai
Hiroshi Yamazaki
Kenji Tomita
Fumio Inai
Previous Patent: Solenoid which comprises the coil by which position Together is carried out in some directions of an...
Next Patent: JPS6023704
Next Patent: JPS6023704